Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PPIA | P62937 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247123 | 0.89 | DPP4 (0.33) | DPP4HDAC4HDAC1GAAHSD17B10 | |
| SCHEMBL8249373 | 0.88 | DPP4 (0.37) | DPP4HDAC4HDAC1GAAHSD17B10 | |
| SCHEMBL8247064 | 0.88 | DPP4 (0.34) | DPP4GAAHSD17B10ALOX15KDM4E | |
| SCHEMBL14216851 | 0.85 | ALDH1A1 (0.33) | DPP4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11975940 | 0.82 | HDAC4 (0.33) | HDAC4HDAC1GAAHSD17B10ALOX15 | |
| SCHEMBL8237425 | 0.81 | CTSB (0.38) | HDAC4HDAC1 | |
| SCHEMBL16938902 | 0.79 | HDAC4 (0.32) | HDAC4HDAC1MEN1KMT2A | |
| SCHEMBL8237792 | 0.79 | PSMB9 (0.38) | GAAHSD17B10ALOX15PPIA | |
| SCHEMBL16639055 | 0.78 | L3MBTL1 (0.36) | — | |
| SCHEMBL13071410 | 0.78 | ALOX15 (0.37) | DPP4HDAC4HDAC1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |