Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238164 | 0.93 | TGFBR1 (0.57) | TGFBR1MAPK14 | |
| SCHEMBL8229446 | 0.82 | TGFBR1 (0.58) | TGFBR1MAPK14 | |
| SCHEMBL8237303 | 0.81 | TGFBR1 (0.59) | TGFBR1 | |
| SCHEMBL8236653 | 0.79 | TGFBR1 (0.60) | TGFBR1MAPK14 | |
| SCHEMBL4791364 | 0.76 | TGFBR1 (0.52) | TGFBR1MAPK14 | |
| SCHEMBL16298331 | 0.70 | TGFBR1 (0.37) | TGFBR1MAPK14 | |
| SCHEMBL8236655 | 0.69 | TGFBR1 (0.50) | TGFBR1MAPK14 | |
| SCHEMBL8236356 | 0.67 | TGFBR1 (0.51) | TGFBR1MAPK14 | |
| SCHEMBL21083428 | 0.67 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL410500 | 0.67 | TGFBR1 (0.65) | TGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076127-A2 | CONDENSED IMIDAZOLES OR PYRAZOLES AND THEIR USE AS TRANSFORMING GROWTH FACTOR MODULATORS | BIOGEN IDEC MA INC (US) | 2007-07-05 | — | — | WO | disclosed |