Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL827361 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1GAAEGLN1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL825845 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDLMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL826687 | 0.81 | MEN1 (0.56) | ALDH1A1GAALMNACYP1A2CYP2D6 | |
| SCHEMBL5875862 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAAEGLN1HPGDTSHR | |
| SCHEMBL5875866 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GAAEGLN1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL827101 | 0.76 | TSHR (0.53) | ALDH1A1GAAHPGDTSHRLMNA | |
| SCHEMBL11251592 | 0.76 | CYP1A2 (0.46) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL827558 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1HPGDTSHRCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL826873 | 0.75 | MEN1 (0.51) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11235244 | 0.74 | HRH2 (0.53) | TSHRLMNACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143296-B2 | Thiazole-based compound and inhibitor of T-type calcium channel containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-03-27 | — | — | US | disclosed |
| US-20100179201-A1 | NOVEL THIAZOLE-BASED COMPOUND AND INHIBITOR OF T-TYPE CALCIUM CHANNEL CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179201-A1 | NOVEL THIAZOLE-BASED COMPOUND AND INHIBITOR OF T-TYPE CALCIUM CHANNEL CONTAINING THE SAME | CACNA1G, CACNA1I, CACNA1H | ALDH1A1 4316/4885GAA 2546/4885EGLN1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.