SCHEMBL8238293

SCHEMBL8238293

CC(COC(=O)O)OC(=O)O.CN(C)C(=O)OCC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
CHRNB2 P17787 3/20 0.35
CHRNA4 P43681 3/20 0.35
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
GAA P10253 1/20 0.32
MAPK1 P28482 1/20 0.32
NR1H3 Q13133 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6460994 0.84 HTT (0.40) HTT
SCHEMBL2924441 0.79 HTT (0.48) HTTCHRNB2CHRNA4CHRM2CHRM4
SCHEMBL15053822 0.77 TSHR (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8727210 0.77 TSHR (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15308 0.77 TSHR (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL748244 0.77 TSHR (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
Carbamic Acid SCHEMBL17473082 0.76 HTT (0.42) HTTCHRNB2CHRNA4CHRM2CHRM4
Ethane SCHEMBL10522900 0.75 TSHR (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Fluoride SCHEMBL6427102 0.75 TSHR (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Ammonia Solution, Strong SCHEMBL9513085 0.75 TSHR (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6159640-A Electrolyte system for lithium batteries and use of said system, and method for increasing the safety of lithium batteries HOECHST RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) 2000-12-12 US disclosed