SCHEMBL748244

SCHEMBL748244

C[C@H](COC(=O)O)OC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
ALDH1A1 P00352 1/20 0.33
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM1 P11229 2/20 0.32
TBXA2R P21731 1/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP2C9 P11712 1/20 0.31
GALR3 O60755 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15308 1.00 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL8727210 1.00 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL15053822 1.00 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
Methyl Alcohol SCHEMBL9400635 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Ethane SCHEMBL10522900 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Methane SCHEMBL2179835 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Ammonia Solution, Strong SCHEMBL9513085 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Fluoride SCHEMBL6427102 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL7262572 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Bicarbonate SCHEMBL325795 0.98 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114292297-B Method for preparing antiviral drug tenofovir alafenamide fumarate 福建南方制药股份有限公司 2024-05-10 CN claimed
CN-116854735-A Synthesis method of tenofovir 广西奕安泰药业有限公司 2023-10-10 CN claimed
CN-111943982-B Synthesis process of antiviral drug 山东罗欣药业集团股份有限公司 2023-10-10 CN claimed
CN-114292297-A Method for preparing antiviral drug tenofovir alafenamide fumarate 福建南方制药股份有限公司 2022-04-08 CN claimed
CN-110078765-A A kind of preparation method of tenofovir dipivoxil 南京望知星医药科技有限公司 2019-08-02 CN claimed
CN-104910209-A Tenofovir preparation method SHANGHAI ACEBRIGHT PHARMACEUTICALS GROUP CO LTD 2015-09-16 CN claimed
CN-103408593-B The preparation method of tynofovir SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2015-08-26 CN claimed
CN-104277027-A Preparation method of (R)-propylene carbonate YANGZHOU SANYOU SYNTHESIS CHEMICAL CO LTD 2015-01-14 CN claimed
CN-104262397-A Preparation method of high-purity tenofovir ZHEJIANG PROVINCE TIANTAI COUNTY AURISCO PHARMACEUTICAL CO LTD 2015-01-07 CN claimed
CN-103864847-A Process for preparing tenofovir SHANGHAI DESANO CHEMICAL PHARM 2014-06-18 CN claimed
CN-102060876-B Preparation method for tenofovir ZHONGSHAN BAILING BIO TECH CO LTD 2014-06-11 CN claimed
CN-103408593-A Preparation method of tenofovir SUZHOU MIRACPHARMA TECHNOLOGY CO LTD 2013-11-27 CN claimed
CN-102391239-B Preparation method of (R)-propene carbonate SHANGHAI KELY BIO PHARMACEUTICAL CO LTD 2013-08-21 CN claimed
CN-102391239-A Preparation method of (R)-propene carbonate SHANGHAI KELI BIOLOG MEDICAL CO LTD 2012-03-28 CN claimed
CN-102219805-A Novel production process of tenofovir SUZHOU TENGLONG BIO PHARMACEUTICAL TECHNOLOGY CO LTD 2011-10-19 CN claimed
CN-101516866-A Method of production of enantiomer-enriched alkylene carbonates EVONIK DEGUSSA GMBH (DE) 2009-08-26 CN claimed
EP-2074109-A1 METHOD OF PRODUCTION OF ENANTIOMER-ENRICHED ALKYLENE CARBONATES Evonik Degussa GmbH (DE) 2009-07-01 EP claimed
WO-2008034685-A1 METHOD OF PRODUCTION OF ENANTIOMER-ENRICHED ALKYLENE CARBONATES EVONIK DEGUSSA GMBH (DE) 2008-03-27 WO claimed
US-12398162-B2 Guanine analogs as telomerase substrates and telomere length affectors GERON CORPORATION (US) 2025-08-26 US disclosed
US-5733788-A PURIFICATION, LIQUID CHROMATOGRAPHY GILEAD SCIENCES, INC. (US) 1998-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398162-B2 Guanine analogs as telomerase substrates and telomere length affectors TERT, POT1, TERF2 TSHR 2606/4885ALDH1A1 3248/4885CHRM2 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.