Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9513085

CC(COC(=O)O)OC(=O)O.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.35
ALDH1A1 P00352 1/20 0.32
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM1 P11229 2/20 0.31
TBXA2R P21731 1/20 0.31
MAPT P10636 2/20 0.31
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30
GALR3 O60755 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL748244 0.98 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL8727210 0.98 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL15053822 0.98 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL15308 0.98 TSHR (0.37) TSHRALDH1A1CHRM2CHRM4CHRM1
Methyl Alcohol SCHEMBL9400635 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Ethane SCHEMBL10522900 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Methane SCHEMBL2179835 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL7262572 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Fluoride SCHEMBL6427102 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1
Bicarbonate SCHEMBL325795 0.95 TSHR (0.35) TSHRALDH1A1CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408187-B1 PIGMENT DISPERSANT IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-06 EP disclosed
EP-0408187-A1 Pigment dispersant IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-16 EP disclosed
US-4946507-A CATHODIC ELECTRODEPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-07 US disclosed