Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 8/20 | 0.56 |
| ▸ | CA1 | P00915 | 8/20 | 0.56 |
| ▸ | CA2 | P00918 | 8/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PAK4 | O96013 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238853 | 0.84 | DDX3X (0.61) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL13380966 | 0.81 | DDX3X (1.00) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL13380962 | 0.81 | DDX3X (0.93) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8241328 | 0.77 | DDX3X (0.59) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8909166 | 0.75 | DDX3X (0.85) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8908392 | 0.75 | DDX3X (0.85) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL11913707 | 0.75 | DDX3X (0.69) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL13380954 | 0.74 | MAPT (1.00) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL11913667 | 0.74 | DDX3X (1.00) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL14527789 | 0.73 | DDX3X (0.61) | DDX3XMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790345-A1 | Triazin beta-secretase inhibitors | Esbatech AG (CH) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007051333-A1 | TRIAZINE BETA-SECRETASE INHIBITORS | ONCALIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |