Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527789 | 0.89 | DDX3X (0.61) | DDX3XKMT2AMAPTMEN1HTT | |
| SCHEMBL8241328 | 0.78 | DDX3X (0.59) | DDX3XKMT2AMAPTMEN1HTT | |
| SCHEMBL8265458 | 0.75 | ALDH1A1 (0.56) | KMT2AMAPTMEN1HTTKDM4E | |
| SCHEMBL14264133 | 0.73 | ALDH1A1 (0.66) | KMT2AMAPTMEN1KDM4ERAB9A | |
| SCHEMBL14264134 | 0.71 | ALDH1A1 (0.71) | KMT2AMAPTMEN1KDM4ERAB9A | |
| SCHEMBL31398568 | 0.70 | KMT2A (0.62) | KMT2AMAPTMEN1HTTTDP1 | |
| SCHEMBL30568815 | 0.70 | KMT2A (0.62) | KMT2AMAPTMEN1HTTTDP1 | |
| SCHEMBL8238853 | 0.69 | DDX3X (0.61) | DDX3XKMT2AMAPTMEN1HTT | |
| SCHEMBL8231988 | 0.69 | DDX3X (0.61) | DDX3XKMT2AMAPTMEN1HTT | |
| SCHEMBL11913667 | 0.68 | DDX3X (1.00) | DDX3XKMT2AMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051333-A1 | TRIAZINE BETA-SECRETASE INHIBITORS | ONCALIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |