Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001744 | 0.88 | ACHE (0.39) | HSD11B1MAPK1OPRM1EGFRPOLB | |
| SCHEMBL8272139 | 0.88 | ACHE (0.39) | HSD11B1MAPK1OPRM1EGFRPOLB | |
| SCHEMBL2026452 | 0.83 | PIK3CG (0.40) | PIK3CGHSD11B1MAPK1OPRM1PIK3CD | |
| SCHEMBL2025196 | 0.83 | PIK3CG (0.40) | PIK3CGHSD11B1MAPK1OPRM1PIK3CD | |
| SCHEMBL12413553 | 0.81 | HSD11B1 (0.37) | PIK3CGHSD11B1MAPK1MAPT | |
| SCHEMBL2024712 | 0.78 | PIK3CG (0.43) | PIK3CGHSD11B1MAPK1PIK3CDPIK3R1 | |
| SCHEMBL2024709 | 0.78 | PIK3CG (0.43) | PIK3CGHSD11B1MAPK1PIK3CDPIK3R1 | |
| SCHEMBL8272138 | 0.78 | HSD11B1 (0.41) | PIK3CGHSD11B1MAPK1OPRM1PIK3CD | |
| SCHEMBL2024711 | 0.78 | HSD11B1 (0.41) | PIK3CGHSD11B1MAPK1OPRM1PIK3CD | |
| SCHEMBL13628484 | 0.76 | HSD11B1 (0.41) | PIK3CGHSD11B1MAPK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021309-A1 | SUBSTITUTED ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (SE) | 2007-02-22 | — | — | WO | disclosed |