Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807452 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GPR35TTRHTTMEN1 | |
| SCHEMBL18305040 | 0.79 | GPR35 (0.43) | ALDH1A1GPR35TTRHTTMEN1 | |
| SCHEMBL30413519 | 0.79 | GPR35 (0.43) | ALDH1A1GPR35TTRHTTMEN1 | |
| SCHEMBL19135896 | 0.68 | SMN1; SMN2 (0.37) | ALDH1A1GPR35HTTMEN1KMT2A | |
| SCHEMBL21845537 | 0.68 | GPR35 (0.43) | ALDH1A1GPR35TTRHTTMEN1 | |
| SCHEMBL3211912 | 0.68 | S1PR4 (0.41) | ALDH1A1GPR35HTTMEN1KMT2A | |
| SCHEMBL31347163 | 0.67 | ALDH1A1 (0.43) | ALDH1A1GPR35HTTMEN1KMT2A | |
| SCHEMBL28437715 | 0.67 | GPR35 (0.47) | ALDH1A1GPR35TTRMEN1KMT2A | |
| SCHEMBL1807427 | 0.67 | ALDH1A1 (0.43) | ALDH1A1GPR35HTTMEN1KMT2A | |
| SCHEMBL24568079 | 0.67 | S1PR4 (0.43) | HTTMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |