Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242143 | 0.87 | PIK3C3 (0.39) | PIK3C3HTR6PTPRBBCHECYP2C19 | |
| SCHEMBL8233595 | 0.79 | RORC (0.39) | HTR6 | |
| SCHEMBL8233993 | 0.77 | AKT1 (0.45) | PIK3C3HTR6BCHEAKT1MEN1 | |
| SCHEMBL8240354 | 0.77 | AKT1 (0.40) | HTR6AKT1SCN9A | |
| SCHEMBL30134921 | 0.75 | EGFR (0.48) | PIK3C3MEN1POLBKMT2ASCN9A | |
| SCHEMBL30134898 | 0.75 | EGFR (0.46) | PIK3C3CA1CA2MEN1POLB | |
| SCHEMBL8242925 | 0.74 | PIK3C3 (0.42) | PIK3C3HTR6BCHECA1AKT1 | |
| SCHEMBL30135242 | 0.74 | CIT (0.43) | PIK3C3MEN1POLBKMT2A | |
| SCHEMBL30134934 | 0.74 | CIT (0.43) | PIK3C3MEN1POLBKMT2A | |
| SCHEMBL30135091 | 0.74 | EGFR (0.44) | PIK3C3MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076423-A2 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |