Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273078 | 0.86 | MAPK1 (0.36) | MAPK1KDM4EHSD17B10POLBMAPT | |
| SCHEMBL13409397 | 0.83 | MAPK1 (0.35) | MAPK1KDM4EHSD17B10POLBMAPT | |
| SCHEMBL8130016 | 0.83 | KDM4E (0.41) | MAPK1KDM4EHSD17B10POLBMAPT | |
| SCHEMBL8247673 | 0.68 | ADORA2A (0.39) | MAPK1KDM4EHSD17B10POLBELANE | |
| SCHEMBL14853028 | 0.67 | SMN1; SMN2 (0.36) | MAPK1ELANEPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3054261 | 0.66 | MAPT (0.37) | MAPK1KDM4EHSD17B10POLBMAPT | |
| SCHEMBL8272632 | 0.66 | MAPT (0.43) | MAPK1KDM4EHSD17B10MAPTELANE | |
| SCHEMBL8273081 | 0.66 | MAPT (0.57) | KDM4EMAPTRXFP1ELANESMN1; SMN2 | |
| SCHEMBL5942127 | 0.65 | NOS3 (0.43) | MAPK1MAPTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8271690 | 0.65 | MAPT (0.43) | KDM4EHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009227-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-25 | — | — | WO | disclosed |