Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240581 | 0.86 | MAPK1 (0.37) | MAPK1KDM4EHSD17B10ELANENOTUM | |
| SCHEMBL8130016 | 0.82 | KDM4E (0.41) | MAPK1KDM4EHSD17B10ELANENOTUM | |
| SCHEMBL13409397 | 0.82 | MAPK1 (0.35) | MAPK1KDM4EHSD17B10ELANENOTUM | |
| SCHEMBL8274167 | 0.69 | ADORA2A (0.41) | ELANE | |
| SCHEMBL8271698 | 0.68 | KMT2A (0.46) | KDM4EELANEMAPTRXFP1SMN1; SMN2 | |
| SCHEMBL8272632 | 0.65 | MAPT (0.43) | MAPK1KDM4EHSD17B10ELANEMAPT | |
| SCHEMBL4469982 | 0.63 | SMN1; SMN2 (0.46) | MAPK1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL1421836 | 0.63 | SMN1; SMN2 (0.42) | MAPK1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL8273088 | 0.63 | MAPT (0.36) | KDM4EMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8272310 | 0.63 | KDM4E (0.47) | KDM4EHSD17B10POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000085-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |