Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958056 | 0.89 | CCR6 (0.68) | CCR6PDE10APOLBKDM4ELMNA | |
| SCHEMBL28019600 | 0.87 | CCR6 (0.67) | CCR6PDE10APOLBKDM4ELMNA | |
| SCHEMBL5525815 | 0.87 | PDE10A (0.65) | CCR6PDE10APOLBKDM4ELMNA | |
| SCHEMBL29788466 | 0.80 | DHODH (0.80) | PDE10APOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL4017739 | 0.80 | DHODH (0.80) | PDE10APOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL6429299 | 0.79 | KDM4E (0.80) | CCR6PDE10APOLBKDM4ELMNA | |
| SCHEMBL11810641 | 0.77 | PDE10A (0.70) | PDE10APOLBKDM4ELMNAHTT | |
| SCHEMBL13460561 | 0.76 | DHODH (0.59) | PDE10APOLBKDM4ELMNAHTT | |
| SCHEMBL3228463 | 0.76 | AURKA (0.69) | PDE10APOLBKDM4ELMNAHTT | |
| SCHEMBL27982961 | 0.75 | PDE10A (0.56) | CCR6PDE10APOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |