Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299133 | 1.00 | NPSR1 (0.33) | NPSR1ALDH1A1POLBFAAHNAAA | |
| SCHEMBL9972392 | 0.90 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL628012 | 0.86 | NPSR1 (0.33) | NPSR1ALDH1A1POLBFAAHNAAA | |
| SCHEMBL3731484 | 0.86 | NPSR1 (0.33) | NPSR1ALDH1A1POLBFAAHNAAA | |
| SCHEMBL10298837 | 0.83 | NPSR1 (0.32) | NPSR1ALDH1A1POLBFAAHNAAA | |
| SCHEMBL2435477 | 0.80 | MAPK1 (0.35) | NPSR1HSD17B10 | |
| SCHEMBL2756144 | 0.78 | — | — | |
| SCHEMBL8228395 | 0.76 | CCR2 (0.33) | — | |
| SCHEMBL26452827 | 0.76 | NPSR1 (0.36) | NPSR1ALDH1A1POLBFAAHNAAA | |
| SCHEMBL10298829 | 0.73 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696226-B2 | HIV protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2010-04-13 | — | — | US | disclosed |
| US-20050159469-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159469-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | NPSR1 4034/4885ALDH1A1 2920/4885POLB 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.