Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755767 | 0.73 | HPGD (0.49) | ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL17755772 | 0.73 | HPGD (0.49) | ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL11752890 | 0.72 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL17755778 | 0.71 | LMNA (0.44) | GAAKDM4EMAPTTSHRRAB9A | |
| SCHEMBL12262674 | 0.71 | ALDH1A1 (0.85) | EDNRAALDH1A1RXFP1GAAKDM4E | |
| SCHEMBL6017475 | 0.70 | HTT (0.71) | ALDH1A1RXFP1GAAPOLBMAPT | |
| SCHEMBL7857544 | 0.69 | KDM4E (0.66) | EDNRAALDH1A1RXFP1EDNRBGAA | |
| SCHEMBL6959046 | 0.68 | EDNRA (0.71) | EDNRAALDH1A1RXFP1EDNRBKDM4E | |
| SCHEMBL6151684 | 0.68 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7338921 | 0.68 | EDNRA (0.71) | EDNRAALDH1A1RXFP1EDNRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991427-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | Marsden, John Christopher (GB) | 2000-04-12 | — | — | EP | disclosed |
| EP-0973552-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | Marsden, John Christopher (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998018495-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |
| WO-1998018501-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |