Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271078 | 0.84 | ALDH1A1 (0.51) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11634132 | 0.82 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5139911 | 0.81 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL16691393 | 0.81 | SLC6A4 (0.72) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11026840 | 0.79 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517701 | 0.79 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517976 | 0.79 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14347765 | 0.79 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1201181 | 0.79 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4800365 | 0.78 | SLC6A4 (0.49) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-B1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |