Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.41 |
| ▸ | PRKACA | P17612 | 4/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154646 | 0.86 | ADORA2A (0.50) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8461385 | 0.83 | AHCY (0.51) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL19066616 | 0.73 | AHCY (0.58) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6698657 | 0.71 | AHCY (0.55) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL536759 | 0.71 | AHCY (0.52) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8350372 | 0.70 | PRKACA (0.39) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL724837 | 0.70 | ADORA2A (0.58) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5685760 | 0.70 | AHCY (0.54) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28901883 | 0.69 | AHCY (0.61) | TSHRADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL177772 | 0.69 | AHCY (0.61) | TSHRADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020321-A | Adenosine receptor agonists for the promotion of wound healing | NEW YORK UNIVERSITY (US) | 2000-02-01 | — | — | US | disclosed |