Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242276 | 0.70 | TSHR (0.43) | PRKACAADORA1TSHRADORA3ADORA2A | |
| SCHEMBL8472359 | 0.66 | NT5E (0.48) | ADORA1TSHRADORA3ADORA2AADORA2B | |
| SCHEMBL8481124 | 0.65 | PRKACA (0.49) | PRKACAADORA1TSHRADORA3ADORA2A | |
| SCHEMBL8664263 | 0.62 | ADORA3 (0.47) | PRKACAADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL5944004 | 0.61 | DOT1L (0.61) | PRKACAADORA1TSHRADORA3ADORA2A | |
| SCHEMBL5944101 | 0.60 | ADORA3 (0.56) | PRKACAADORA1TSHRADORA3ADORA2A | |
| SCHEMBL10886606 | 0.59 | AHCY (0.65) | ADORA1TSHRADORA3ADORA2AADORA2B | |
| SCHEMBL5944284 | 0.59 | ADORA3 (0.53) | ADORA1TSHRADORA3ADORA2AADORA2B | |
| SCHEMBL9024927 | 0.59 | PRMT5 (0.58) | ADORA1ADORA3ADORA2AADORA2BMAPK1 | |
| SCHEMBL9024944 | 0.59 | PRMT5 (0.58) | ADORA1ADORA3ADORA2AADORA2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932558-A | PROMOTE MIGRATION OF ENDOTHELIAL CELLS, FIBROBLASTS AND EPITHELIAL CELLS | NEW YORK UNIVERSITY (US) | 1999-08-03 | — | — | US | disclosed |