Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999414 | 0.84 | PYCR1 (0.49) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL15692215 | 0.80 | KMT2A (0.61) | PYCR1KMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL14238298 | 0.79 | PYCR1 (0.44) | TGM2PYCR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL841278 | 0.78 | L3MBTL1 (0.50) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL840310 | 0.77 | MEN1 (0.50) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL20658835 | 0.77 | L3MBTL1 (0.49) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3856253 | 0.76 | SMN1; SMN2 (0.59) | L3MBTL1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL31248387 | 0.75 | L3MBTL1 (0.60) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9295394 | 0.72 | SPHK2 (0.47) | TGM2PYCR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8151807 | 0.72 | PYCR1 (0.64) | TGM2PYCR1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |