Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494432 | 1.00 | MAPT (0.41) | MAPTCNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL8215633 | 0.90 | KIF11 (0.50) | MAPTCNR2CNR1EPHX2KIF11 | |
| SCHEMBL8212418 | 0.83 | TAAR1 (0.49) | MAPTALDH1A1NPSR1EPHX2KMT2A | |
| SCHEMBL8216222 | 0.75 | NPC1 (0.50) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8216081 | 0.74 | MAPT (0.56) | MAPTALDH1A1NPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL8212617 | 0.74 | NPC1 (0.54) | MAPTALDH1A1NPSR1EPHX2KMT2A | |
| SCHEMBL8212684 | 0.74 | ROCK1 (0.38) | MAPTALDH1A1NPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL8207992 | 0.73 | KIF11 (0.58) | MAPTALDH1A1EPHX2KIF11KMT2A | |
| SCHEMBL8215635 | 0.73 | NPC1 (0.61) | MAPTCNR2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8212593 | 0.72 | SMN1; SMN2 (0.47) | MAPTALDH1A1NPSR1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064732-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |