SCHEMBL8212418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8243196	0.86	TAAR1 (0.44)	TAAR1HPGDMAPK1FPR2EPHX2
	SCHEMBL8208836	0.85	MEN1 (0.52)	HPGDMAPTKMT2ASMN1; SMN2ALDH1A1
	SCHEMBL8215633	0.85	KIF11 (0.50)	HPGDFPR2EPHX2MAPTKMT2A
	SCHEMBL8212593	0.85	SMN1; SMN2 (0.47)	FPR2MAPTKMT2ANPSR1USP2
	SCHEMBL14494432	0.83	MAPT (0.41)	FPR2EPHX2MAPTKMT2ANPSR1
	SCHEMBL8243200	0.83	MAPT (0.41)	FPR2EPHX2MAPTKMT2ANPSR1
	SCHEMBL8212684	0.79	ROCK1 (0.38)	MAPTKMT2ANPSR1SMN1; SMN2ALDH1A1
	SCHEMBL8218401	0.77	MAPT (0.53)	MAPK1MAPTKMT2ANPSR1USP2
	SCHEMBL8216222	0.77	NPC1 (0.50)	MAPTKMT2ASMN1; SMN2NPC1
	SCHEMBL8215800	0.77	TAAR1 (0.63)	TAAR1HPGDMAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.