Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765407 | 0.86 | ALDH1A1 (0.61) | NPC1RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL8251473 | 0.77 | MAPT (0.62) | NPC1RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL2924706 | 0.72 | HPGD (0.54) | NPC1RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL6322177 | 0.66 | SRD5A2 (0.79) | NPC1RAB9AMAPTHPGDHTT | |
| SCHEMBL257653 | 0.66 | ALDH1A1 (0.61) | RAB9AMAPTHPGDALDH1A1HTT | |
| SCHEMBL15100942 | 0.66 | SRD5A2 (0.53) | MAPTHPGDALDH1A1HTTMAPK1 | |
| SCHEMBL13176761 | 0.65 | ATM (0.55) | NPC1RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL15100551 | 0.64 | MAPT (0.63) | NPC1MAPTHPGDALDH1A1HTT | |
| SCHEMBL257368 | 0.64 | SMN1; SMN2 (0.56) | NPC1RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL703716 | 0.63 | HPGD (0.53) | NPC1RAB9AHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138428-A2 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |