Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.58 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 14/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12042599 | 0.87 | ALOX15 (0.60) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL14586319 | 0.87 | VCAM1 (0.67) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL12042598 | 0.86 | ALOX15 (0.62) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL5575964 | 0.84 | ALOX15 (0.64) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL14586314 | 0.82 | VCAM1 (0.53) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL13609378 | 0.81 | VCAM1 (0.60) | ALOX15HPNMAPTSIRT5VCAM1 | |
| Elsibucol SCHEMBL6002307 | 0.81 | VCAM1 (0.73) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL12042584 | 0.81 | ALOX15 (0.68) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL6000617 | 0.80 | VCAM1 (0.73) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL14037559 | 0.80 | VCAM1 (0.70) | ALOX15HPNMAPTSIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044726-A2 | METHODS FOR REDUCING PLATELET ACTIVATION AND FOR THE TREATMENT OF THROMBOTIC EVENTS | ATHEROGENICS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2003039231-A2 | COMPOUNDS AND METHODS FOR TREATING TRANSPLANT REJECTION | ATHEROGENICS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |