Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | GLA | P06280 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FHIT | P49789 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243919 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL4710605 | 0.83 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL4712725 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL4708968 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL13342421 | 0.66 | MAP2K1 (0.66) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL4711181 | 0.64 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL2289558 | 0.63 | ALDH1A1 (0.56) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL4711131 | 0.62 | ALDH1A1 (0.56) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL11325519 | 0.62 | APEX1 (0.37) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL4710676 | 0.61 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045876-A1 | CHROMENONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-04-26 | — | — | WO | disclosed |