SCHEMBL824477

SCHEMBL824477

C=CC(=O)Oc1ccc(C(C)(C)c2ccccc2)cc1C(C)c1cc(C(C)(C)c2ccccc2)ccc1O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.41
ELANE P08246 6/20 0.41
ALDH1A1 P00352 4/20 0.35
ESR1 P03372 4/20 0.35
ESR2 Q92731 3/20 0.35
CYP3A4 P08684 1/20 0.35
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
KDM4E B2RXH2 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 2/20 0.34
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824547 0.82 RORC (0.47) RORCELANEALDH1A1ESR1ESR2
SCHEMBL824502 0.82 CYP3A4 (0.37) RORCELANEESR1CYP3A4SMN1; SMN2
SCHEMBL14173091 0.81 ELANE (0.38) RORCELANEKDM4ETHRATHRB
SCHEMBL51353 0.80 RORC (0.60) RORCALDH1A1ESR1ESR2CYP3A4
SCHEMBL12949863 0.80 KDM4E (0.40) ALDH1A1ESR1ESR2CYP3A4CNR1
SCHEMBL14173090 0.79 RORC (0.54) RORCELANEKDM4ESMN1; SMN2GAA
SCHEMBL824541 0.76 MAPT (0.41) GAATHRBMEN1HTTKMT2A
SCHEMBL1343545 0.75 RORC (0.54) RORCALDH1A1ESR1ESR2CYP3A4
SCHEMBL1344986 0.75 RORC (0.54) RORCALDH1A1ESR1ESR2CYP3A4
SCHEMBL1345272 0.75 RORC (0.54) RORCALDH1A1ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-20100047480-A1 CELLULOSE ESTER PELLETS, CELLULOSE ESTER FILM, MANUFACTURING METHOD OF CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY C/O KONICA MINOLTA OPTO, INC. (JP) 2010-02-25 US disclosed
US-20100047480-A1 CELLULOSE ESTER PELLETS, CELLULOSE ESTER FILM, MANUFACTURING METHOD OF CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY C/O KONICA MINOLTA OPTO, INC. (JP) 2010-02-25 US disclosed