SCHEMBL824547

SCHEMBL824547

CCCC(=O)Oc1ccc(C(C)(C)c2ccccc2)cc1C(C)c1cc(C(C)(C)c2ccccc2)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.47
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 6/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
ELANE P08246 4/20 0.36
RECQL P46063 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
ESR1 P03372 3/20 0.35
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 1/20 0.35
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
LMNA P02545 3/20 0.34
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824477 0.82 RORC (0.41) RORCKDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL51353 0.80 RORC (0.60) RORCALOX15MEN1KMT2AALDH1A1
SCHEMBL824480 0.77 ALOX15 (0.40) RORCALOX15KDM4EMEN1KMT2A
SCHEMBL1345546 0.75 RORC (0.54) RORCALOX15KDM4EALDH1A1TDP1
SCHEMBL1344986 0.75 RORC (0.54) RORCALOX15KDM4EALDH1A1TDP1
SCHEMBL1345272 0.75 RORC (0.54) RORCALOX15KDM4EALDH1A1TDP1
SCHEMBL1343545 0.75 RORC (0.54) RORCALOX15KDM4EALDH1A1TDP1
SCHEMBL4595074 0.73 RORC (0.58) RORCALOX15ALDH1A1ESR1ESR2
SCHEMBL27912180 0.72 RORC (0.60) RORCALOX15ALDH1A1ESR1ESR2
SCHEMBL27665795 0.71 RORC (0.49) RORCALOX15KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-8142864-B2 Cellulose ester pellets, cellulose ester film, manufacturing method of cellulose ester film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-03-27 US disclosed
US-20100047480-A1 CELLULOSE ESTER PELLETS, CELLULOSE ESTER FILM, MANUFACTURING METHOD OF CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY C/O KONICA MINOLTA OPTO, INC. (JP) 2010-02-25 US disclosed
US-20100047480-A1 CELLULOSE ESTER PELLETS, CELLULOSE ESTER FILM, MANUFACTURING METHOD OF CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY C/O KONICA MINOLTA OPTO, INC. (JP) 2010-02-25 US disclosed