Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4710612 | 0.99 | FHIT (0.56) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL4709626 | 0.85 | KDM4E (0.64) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL4712428 | 0.84 | KDM4E (0.61) | FHITKDM4EALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL4710861 | 0.83 | KDM4E (0.60) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL10999716 | 0.81 | MAPT (0.46) | KDM4EALDH1A1TDP1RXFP1HPGD | |
| Hydrochloric Acid SCHEMBL10509505 | 0.81 | MAPT (0.45) | KDM4EALDH1A1TDP1HPGDKMT2A | |
| SCHEMBL4710636 | 0.79 | KDM4E (0.62) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL4710578 | 0.78 | KDM4E (0.63) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL4711828 | 0.77 | KDM4E (0.56) | FHITKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL4711123 | 0.74 | KDM4E (0.64) | FHITKDM4EALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045876-A1 | CHROMENONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-04-26 | — | — | WO | disclosed |