Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 12/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509452 | 0.88 | CTSB (0.41) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL15509453 | 0.88 | CTSB (0.41) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL7914476 | 0.88 | CTSB (0.41) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL15509451 | 0.88 | CTSB (0.41) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL8249221 | 0.88 | CTSB (0.41) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL19870671 | 0.88 | CYP3A4 (0.37) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL12784320 | 0.87 | PSMB8 (0.31) | CTSBPSMB9PSMB8 | |
| SCHEMBL8243810 | 0.85 | PSMB9 (0.33) | CTSBPSMB9PSMB8CTSS | |
| SCHEMBL1645323 | 0.84 | CTSB (0.34) | CTSBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1645325 | 0.84 | CTSB (0.34) | CTSBKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |