SCHEMBL824684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL824626	0.90	AR (0.51)	PIK3C3JAK1JAK3HSD17B10PDK2
	SCHEMBL824620	0.90	AR (0.48)	PIK3C3JAK1JAK3ALDH1A1HSD17B10
	SCHEMBL824897	0.89	AR (0.50)	PIK3C3JAK1JAK3HSD17B10PDK2
	SCHEMBL824773	0.88	AR (0.41)	PIK3C3JAK1JAK3PRKDCCYP1A2
	SCHEMBL824758	0.88	AR (0.41)	PIK3C3JAK1JAK3PRKDCCYP1A2
	SCHEMBL824694	0.87	PIK3C3 (0.41)	PIK3C3JAK1JAK3PRKDCALDH1A1
	SCHEMBL3544038	0.86	PIK3C3 (0.46)	PIK3C3JAK1JAK3PRKDCAPAF1
	SCHEMBL824947	0.85	TDO2 (0.51)	PIK3C3PRKDCAPAF1CDC25BCASP3
	SCHEMBL824638	0.85	PIK3C3 (0.41)	PIK3C3JAK1JAK3CYP3A4PDK2
	SCHEMBL824670	0.85	AR (0.39)	PIK3C3JAK1JAK3PRKDCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.