Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247259 | 0.71 | TSHR (0.46) | GLANPSR1 | |
| SCHEMBL14904524 | 0.68 | — | — | |
| SCHEMBL14392214 | 0.64 | LMNA (0.33) | NPSR1 | |
| SCHEMBL14847327 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL13191206 | 0.64 | — | — | |
| SCHEMBL3091631 | 0.62 | GLA (0.61) | GLANPSR1 | |
| SCHEMBL21999082 | 0.61 | GLA (0.43) | GLANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL3101147 | 0.59 | GLA (0.47) | GLANPSR1 | |
| SCHEMBL5980626 | 0.58 | TSHR (0.33) | — | |
| SCHEMBL31607391 | 0.58 | GLA (0.48) | GLANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008037-A1 | NOVEL CHROMEN-2-ONE BASED HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY, THE PREPARATION THEREOF AND A COMPOSITION CONTAINING THE SAME FOR TREATING INFLAMMATORY DISEASE | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2007-01-18 | — | — | WO | disclosed |