Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091631 | 0.85 | GLA (0.61) | TSHRKMT2AGLANPSR1LOXL2 | |
| SCHEMBL3097535 | 0.80 | GLA (0.48) | KMT2AGLANPSR1MAOA | |
| SCHEMBL17171323 | 0.78 | GLA (0.41) | TSHRKMT2AGLANPSR1KCNH2 | |
| SCHEMBL8240783 | 0.74 | CYP1A2 (0.43) | TSHRKMT2ALOXL2CYP1A2CYP2C19 | |
| SCHEMBL3092797 | 0.72 | GLA (0.47) | GLANPSR1HRH3CYP1A2 | |
| SCHEMBL679340 | 0.72 | LOXL2 (0.46) | TSHRKMT2AKCNJ1LOXL2CYP1A2 | |
| SCHEMBL8247161 | 0.71 | GLA (0.32) | GLANPSR1 | |
| SCHEMBL3292782 | 0.71 | TSHR (0.75) | TSHRKCNH2KCNJ1LOXL2HRH3 | |
| SCHEMBL17171322 | 0.70 | SMN1; SMN2 (0.43) | TSHRKMT2AKCNH2KCNJ1LOXL2 | |
| SCHEMBL28528292 | 0.70 | TSHR (0.53) | TSHRKCNH2KCNJ1LOXL2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008037-A1 | NOVEL CHROMEN-2-ONE BASED HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY, THE PREPARATION THEREOF AND A COMPOSITION CONTAINING THE SAME FOR TREATING INFLAMMATORY DISEASE | JEIL PHARMACEUTICAL CO., LTD. (KR) | 2007-01-18 | — | — | WO | disclosed |