Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GALR2 | O43603 | 7/20 | 0.41 |
| ▸ | GALR1 | P47211 | 4/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244045 | 0.83 | GALR2 (0.54) | LMNAMAPTGALR2GALR1 | |
| SCHEMBL6352332 | 0.83 | LMNA (0.41) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL3246394 | 0.81 | MAPT (0.57) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL3244303 | 0.80 | LMNA (0.49) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL8253195 | 0.79 | MAPT (0.48) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL8254119 | 0.78 | KDM4E (0.48) | LMNAMAPTGALR2GALR1SMN1; SMN2 | |
| SCHEMBL8256643 | 0.78 | MAPT (0.48) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL3242771 | 0.78 | LMNA (0.49) | LMNAMAPTGALR2GALR1CCNE1 | |
| SCHEMBL3262414 | 0.78 | MAPT (0.50) | LMNAMAPTGALR2GALR1CYP2C9 | |
| SCHEMBL6790642 | 0.78 | LMNA (0.47) | LMNAMAPTGALR2GALR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | GALR3, GALR2, GALR1 | LMNA 3975/4885MAPT 2638/4885GALR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.