Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165622 | 0.94 | MMP13 (0.39) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL8225272 | 0.93 | MMP13 (0.40) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10162252 | 0.92 | MMP13 (0.40) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10165624 | 0.92 | MMP13 (0.39) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL8256775 | 0.92 | MMP13 (0.39) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10162208 | 0.92 | MMP13 (0.41) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10209873 | 0.91 | MMP13 (0.40) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL8255580 | 0.91 | MMP13 (0.39) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10165620 | 0.90 | MMP13 (0.38) | MMP13MAPK1PDE2ARPS6KA1DGAT1 | |
| SCHEMBL10165797 | 0.88 | MMP13 (0.46) | MMP13MAPK1PDE2ARPS6KA1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |