Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248130 | 0.76 | HDAC1 (0.56) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL8256750 | 0.75 | HDAC1 (0.57) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL8256489 | 0.74 | HDAC1 (0.47) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1779270 | 0.72 | HDAC1 (0.58) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1779275 | 0.72 | HDAC1 (0.58) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1779274 | 0.72 | HDAC1 (0.58) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL1779648 | 0.72 | HDAC1 (0.58) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL20023 | 0.71 | HDAC1 (0.64) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL2733125 | 0.71 | HDAC1 (0.64) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL20432791 | 0.70 | HDAC1 (0.55) | HDAC1HDAC6HDAC8HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101456-A1 | BICYCLIC HETEROCYCLES HYDROXAMATE COMPOUNDS USEFUL AS HISTONE DEACETYLASE (HDAC) INHIBITORS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |