Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624408 | 0.82 | MMP2 (0.42) | MMP2ANPEP | |
| SCHEMBL25879033 | 0.82 | CTSV (0.33) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL25076008 | 0.82 | CTSV (0.33) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8284168 | 0.82 | — | — | |
| SCHEMBL11950480 | 0.79 | BRD4 (0.31) | — | |
| SCHEMBL8232300 | 0.77 | CYP1A2 (0.40) | MMP2ANPEP | |
| SCHEMBL9005821 | 0.77 | CYP1A2 (0.40) | MMP2ANPEP | |
| SCHEMBL8249467 | 0.77 | CYP1A2 (0.40) | MMP2ANPEP | |
| SCHEMBL24710114 | 0.77 | CTSV (0.34) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL24209768 | 0.77 | DPP4 (0.39) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130666-A2 | MEDICAMENTS AND METHODS COMBINING A HCV PROTEASE INHIBITOR AND AN AKR COMPETITOR | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |