Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 19/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078016 | 0.89 | HTR4 (0.45) | HTR4HTR3A | |
| SCHEMBL2079397 | 0.86 | HTR4 (0.46) | HTR4HTR3A | |
| SCHEMBL2538722 | 0.78 | HTR4 (0.74) | HTR4HTR3A | |
| SCHEMBL2080088 | 0.76 | HTR4 (0.61) | HTR4 | |
| SCHEMBL2078113 | 0.76 | HTR4 (0.60) | HTR4 | |
| SCHEMBL2078749 | 0.76 | HTR4 (0.67) | HTR4 | |
| SCHEMBL2078067 | 0.75 | HTR4 (0.64) | HTR4 | |
| SCHEMBL4598804 | 0.74 | HTR4 (0.63) | HTR4 | |
| SCHEMBL2078008 | 0.74 | HTR4 (0.43) | HTR4 | |
| SCHEMBL2537523 | 0.74 | HTR4 (0.62) | HTR4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010390-A1 | INDAZOLECARBOXAMIDE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS | PFIZER JAPAN INC. (JP) | 2007-01-25 | — | — | WO | disclosed |