Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 0.74 |
| ▸ | HTR3A | P46098 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261477 | 0.85 | HTR4 (1.00) | HTR4 | |
| SCHEMBL8039331 | 0.85 | HTR4 (1.00) | HTR4 | |
| SCHEMBL12227452 | 0.85 | HTR4 (1.00) | HTR4 | |
| Trifluoroacetic Acid SCHEMBL2261833 | 0.82 | HTR4 (0.88) | HTR4 | |
| SCHEMBL2537523 | 0.82 | HTR4 (0.62) | HTR4HTR3A | |
| SCHEMBL8717474 | 0.80 | HTR4 (0.63) | HTR4HTR3A | |
| SCHEMBL8717486 | 0.80 | HTR4 (0.63) | HTR4HTR3A | |
| SCHEMBL2538008 | 0.80 | HTR4 (0.60) | HTR4HTR3A | |
| SCHEMBL2079397 | 0.78 | HTR4 (0.46) | HTR4HTR3A | |
| SCHEMBL8248204 | 0.78 | HTR4 (0.46) | HTR4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044045-B2 | Indazole-carboxamide compounds as 5-HT4 receptor agonists | THERAVANCE, INC. (US) | 2011-10-25 | — | — | US | disclosed |