Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CTPS1 | P17812 | 7/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245297 | 0.85 | PDE5A (0.54) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8250466 | 0.84 | HTT (0.47) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8249057 | 0.84 | HDAC1 (0.53) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL3603106 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8246412 | 0.81 | HDAC3 (0.54) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8248018 | 0.81 | TSHR (0.49) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL13316882 | 0.80 | CSNK1D (0.53) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8247956 | 0.80 | HTT (0.46) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL5604178 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTCTPS1PDE5A | |
| SCHEMBL3599789 | 0.78 | MAPT (0.46) | HTTALDH1A1LMNAMAPTPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |