Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253104 | 0.87 | ELANE (0.47) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8247440 | 0.86 | ELANE (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8243897 | 0.85 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8280370 | 0.85 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8249374 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8247400 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8245432 | 0.83 | DPP4 (0.49) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12856111 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12605556 | 0.81 | ELANE (0.42) | OPRM1F2F10PRSS1PLG | |
| SCHEMBL8294410 | 0.80 | OPRM1 (0.46) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730142-B1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2011-06-29 | — | — | EP | disclosed |