Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250198 | 1.00 | CTSB (0.36) | CTSBPPP3CBCTSSCYP3A4 | |
| SCHEMBL3277398 | 1.00 | CTSB (0.36) | CTSBPPP3CBCTSSCYP3A4 | |
| SCHEMBL12383127 | 0.91 | CTSS (0.35) | CTSS | |
| SCHEMBL11888410 | 0.91 | CTSS (0.35) | CTSS | |
| SCHEMBL10156683 | 0.90 | CTSS (0.42) | CTSBPPP3CBCTSS | |
| SCHEMBL2449092 | 0.89 | CTSB (0.35) | CTSBPPP3CBCTSSCYP3A4 | |
| SCHEMBL11887180 | 0.89 | CTSB (0.35) | CTSBPPP3CBCTSSCYP3A4 | |
| SCHEMBL13385448 | 0.88 | CTSS (0.35) | CTSS | |
| SCHEMBL2212114 | 0.88 | CTSB (0.41) | CTSBPPP3CBCTSS | |
| SCHEMBL8248937 | 0.88 | CTSB (0.41) | CTSBPPP3CBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017144-A2 | MACROCYLIC INHIBITORS OF HEPATITIS C VIRUS | MEDIVIR AB (SE) | 2007-02-15 | — | — | WO | disclosed |