Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858744 | 0.81 | ALK (0.43) | CYP3A4MAP4K1 | |
| SCHEMBL8249506 | 0.81 | MTNR1B (0.48) | ASAH1CYP3A4 | |
| SCHEMBL8242206 | 0.79 | AXL (0.41) | ASAH1CYP3A4MAP4K1 | |
| SCHEMBL8249503 | 0.78 | CYP3A4 (0.40) | ASAH1CYP3A4MAP4K1 | |
| SCHEMBL413921 | 0.78 | PDPK1 (0.42) | CYP3A4MAP4K1 | |
| SCHEMBL14620858 | 0.77 | ASAH1 (0.34) | ASAH1CYP3A4MAP4K1 | |
| SCHEMBL17170056 | 0.76 | MTNR1A (0.39) | ASAH1CYP3A4MAP4K1 | |
| SCHEMBL859405 | 0.72 | MAPT (0.32) | ASAH1CYP3A4MAP4K1 | |
| SCHEMBL858516 | 0.72 | SNCA (0.39) | CYP3A4MAP4K1JAK2 | |
| SCHEMBL10257418 | 0.71 | MTNR1B (0.43) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002325-A1 | PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |