Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | MDM4 | O15151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241721 | 0.92 | MDM4 (0.49) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL2220884 | 0.90 | KMT2A (0.45) | PTPN1MDM4TP53MMEACE | |
| SCHEMBL25356989 | 0.89 | MDM4 (0.50) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL25356983 | 0.89 | MDM4 (0.50) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL9170986 | 0.85 | MDM4 (0.56) | PTPN1MDM4TP53MDM2CASP3 | |
| SCHEMBL1712911 | 0.84 | ACE (0.53) | MMEACE | |
| SCHEMBL1712913 | 0.84 | ACE (0.53) | MMEACE | |
| SCHEMBL119455 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL1228254 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL118169 | 0.84 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |