SCHEMBL825147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL825236	0.81	AVPR1A (0.62)	HSD11B1OPRM1OPRK1OPRL1OXTR
	SCHEMBL3094597	0.79	KMT2A (0.57)	HSD11B1OXTR
	SCHEMBL614601	0.73	MEN1 (0.61)	HSD11B1AVPR1A
	SCHEMBL825148	0.72	AVPR1A (0.59)	HSD11B1OPRM1OPRK1OPRL1OXTR
	SCHEMBL825277	0.72	OXTR (0.49)	HSD11B1OXTRAVPR1A
	SCHEMBL612394	0.72	POLB (0.62)	—
	SCHEMBL828756	0.72	AVPR1A (0.47)	HSD11B1OPRM1OPRK1OPRL1AVPR1A
	SCHEMBL825327	0.72	AVPR1A (0.47)	HSD11B1OPRM1OPRK1OPRL1AVPR1A
	SCHEMBL825201	0.72	AVPR1A (0.48)	HSD11B1OPRM1OPRK1OPRL1AVPR1A
	SCHEMBL825238	0.72	AVPR1A (0.59)	HSD11B1OPRM1OPRK1OPRL1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.