SCHEMBL825227

SCHEMBL825227

Cc1ccc(CN(C)CCN(Cc2ccc(C)cn2)Cc2ccc(C)cn2)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LIN28A Q9H9Z2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CXCR4 P61073 4/20 0.41
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
CHRM5 P08912 2/20 0.41
CHRM1 P11229 2/20 0.41
CHRM3 P20309 2/20 0.41
NPSR1 Q6W5P4 1/20 0.38
HTR1A P08908 3/20 0.38
CYP2D6 P10635 2/20 0.37
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36
CCR8 P51685 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2224542 0.94 KDM4E (0.40) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL14477281 0.91 MAPT (0.48) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL19880122 0.90 TDP1 (0.61) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL825256 0.84 TDP1 (0.43) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL5027155 0.83 CCR1 (0.46) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL31645820 0.83 CCR1 (0.46) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL14665877 0.83 HSD17B10 (0.44) MAPTCXCR4CHRM2CHRM4CHRM5
SCHEMBL5027191 0.81 BCHE (0.44) MAPTSMN1; SMN2LIN28ATDP1CXCR4
SCHEMBL14174792 0.80 CHRNB2 (0.42) MAPTCXCR4CHRM2CHRM4CHRM5
SCHEMBL1333059 0.80 SMN1; SMN2 (0.47) MAPTSMN1; SMN2LIN28ATDP1CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
US-11193038-B2 Drier compositions for alkyd resins ALLNEX AUSTRIA GMBH (AT) 2021-12-07 US disclosed
EP-2760899-B1 COATING COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2020-08-19 EP disclosed
US-20200207895-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2020-07-02 US disclosed
EP-1008645-A1 Detergent bleaching compositions UNILEVER PLC (GB) 2000-06-14 EP disclosed
WO-2000027976-A1 BLEACH AND OXIDATION CATALYST UNILEVER PLC (GB) 2000-05-18 WO disclosed
WO-2000027975-A1 DETERGENT BLEACHING COMPOSITION UNILEVER PLC (GB) 2000-05-18 WO disclosed
EP-1001009-A1 Bleach and oxidation catalyst UNILEVER PLC (GB) 2000-05-17 EP disclosed
WO-2000012667-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2000-03-09 WO disclosed
WO-2000012808-A1 METHOD OF TREATING A TEXTILE UNILEVER PLC (GB) 2000-03-09 WO disclosed