Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.41 |
| ▸ | ITGAV | P06756 | 5/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | NECTIN4 | Q96NY8 | 4/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258073 | 0.99 | CTSL (0.72) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL8256875 | 0.93 | CTSL (0.68) | CTSLDRD1PTGS1PDE4ASSTR1 | |
| SCHEMBL14274733 | 0.92 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14274734 | 0.91 | CTSL (0.78) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14446808 | 0.91 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14446360 | 0.91 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14446065 | 0.91 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14274597 | 0.90 | CTSL (0.79) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14274758 | 0.90 | CTSL (0.78) | CTSLDRD1PTGS1PDE4AKDM4A | |
| SCHEMBL14274595 | 0.89 | CTSL (0.79) | CTSLDRD1PTGS1PDE4AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110185-A2 | ANTIINFECTIVE LIPOPEPTIDES | CUBIST PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |