SCHEMBL825324

SCHEMBL825324

CCN1CCNCC[N+](Cn2cccn2)(Cn2cccn2)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825466 0.86 CHRNA7 (0.34) CHRNA7CHRNA10CHRNA9BRD4CREBBP
SCHEMBL825333 0.85 SOD3 (0.40)
SCHEMBL1969312 0.78 AURKA (0.33) CHRNA7BRD4CREBBP
SCHEMBL825405 0.71 MAPKAPK2 (0.33)
SCHEMBL6204930 0.71 SIGMAR1 (0.35)
SCHEMBL4841885 0.71 KDM1A (0.41) BRD4CREBBP
SCHEMBL825294 0.67 HRH3 (0.46)
SCHEMBL8319416 0.67 TSHR (0.33)
SCHEMBL1332399 0.67 CHRNA7 (0.37) CHRNA7
SCHEMBL5943 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP claimed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO claimed
EP-2582744-A1 ACCELERATOR SOLUTION AND PROCESS FOR CURING CURABLE RESINS Akzo Nobel Chemicals International B.V. (NL) 2013-04-24 EP disclosed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP disclosed
WO-2011157673-A1 ACCELERATOR SOLUTION AND PROCESS FOR CURING CURABLE RESINS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-12-22 WO disclosed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO disclosed