Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 5/20 | 0.39 |
| ▸ | GALR1 | P47211 | 4/20 | 0.39 |
| ▸ | WEE1 | P30291 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247651 | 0.89 | MAPT (0.48) | MAPTUSP2RXFP1GALR2GALR1 | |
| SCHEMBL8256650 | 0.87 | MAPT (0.45) | MAPTPOLBNPSR1USP2GALR2 | |
| SCHEMBL8256912 | 0.85 | EGFR (0.43) | MAPTPOLBNPSR1USP2RXFP1 | |
| SCHEMBL8254467 | 0.85 | MAPT (0.48) | MAPTPOLBNPSR1USP2GALR2 | |
| SCHEMBL8253195 | 0.85 | MAPT (0.48) | MAPTPOLBNPSR1USP2GALR2 | |
| SCHEMBL8253233 | 0.85 | LMNA (0.44) | MAPTNPSR1USP2RXFP1GALR2 | |
| SCHEMBL3236306 | 0.83 | HTR1A (0.41) | MAPTUSP2RXFP1GALR2GALR1 | |
| SCHEMBL8256921 | 0.80 | GALR2 (0.56) | MAPTPOLBGALR2GALR1KMT2A | |
| SCHEMBL8253239 | 0.79 | POLB (0.39) | MAPTPOLBNPSR1GALR2GALR1 | |
| SCHEMBL8256940 | 0.79 | MAPT (0.43) | MAPTPOLBNPSR1GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | GALR3, GALR2, GALR1 | MAPT 2638/4885POLB 2882/4885NPSR1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.