Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 14/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140868 | 0.89 | HRH4 (0.41) | HRH4TRPM8PARP15PARP10MAPT | |
| Hydrochloric Acid SCHEMBL4141190 | 0.88 | HRH4 (0.40) | HRH4TRPM8PARP15PARP10MAPT | |
| SCHEMBL4136167 | 0.85 | HRH4 (0.40) | HRH4TRPM8RXRAPPARGRXRB | |
| SCHEMBL3192272 | 0.78 | RXRA (0.43) | HRH4TRPM8RXRAPPARGRXRB | |
| SCHEMBL4131770 | 0.77 | HRH4 (0.34) | HRH4TRPM8PARP15PARP10RXRA | |
| SCHEMBL4139481 | 0.77 | RXRA (0.41) | HRH4RXRA | |
| SCHEMBL7945335 | 0.76 | HTT (0.47) | MAPTRXRARXRBRXRG | |
| SCHEMBL3215147 | 0.75 | TSHR (0.46) | HRH4TRPM8PARP15PARP10RXRA | |
| SCHEMBL3125823 | 0.75 | TSHR (0.52) | HRH4TRPM8RXRAPPARGRXRB | |
| SCHEMBL4132244 | 0.75 | HRH4 (0.38) | HRH4TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135828-A2 | TRISUBSTITUTED AMINES AS PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-12-21 | — | — | WO | disclosed |