Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | UBE2N | P61088 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212259 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL11014719 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3714175 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3714845 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL9311753 | 1.00 | SPHK1 (0.62) | SPHK1CYP2D6LMNAGMNNPOLB | |
| Bromide SCHEMBL28243688 | 0.97 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27980409 | 0.97 | SPHK1 (0.58) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL22806314 | 0.88 | SPHK1 (0.68) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL22805047 | 0.88 | SPHK1 (0.68) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL22804794 | 0.88 | SPHK1 (0.68) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621986-A1 | FLEXIBLE POLYURETHANE FOAMS | Dow Global Technologies LLC (US) | 2013-08-07 | — | — | EP | claimed |
| WO-2012044616-A1 | FLEXIBLE POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | WO | claimed |
| EP-1620483-A1 | VEGETABLE OIL BASED POLYOLS AND POLYURETHANES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004096882-A1 | VEGETABLE OIL BASED POLYOLS AND POLYURETHANES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| EP-0026984-B1 | CHEMICAL PRODUCT, PROCESS FOR THE PREPARATION AND COATING COMPOSITIONS THEREOF AND ARTICLES COATED THEREWITH | HENKEL CORPORATION (a Delaware corp.) (US) | 1983-08-17 | — | — | EP | claimed |
| EP-0035820-A2 | Novel quinoline derivatives, pharmaceutical compositions containing such compounds, and method for the preparation of these compounds | ACF CHEMIEFARMA NV (NL) | 1981-09-16 | — | — | EP | claimed |
| EP-0026984-A1 | Chemical product, process for the preparation and coating compositions thereof and articles coated therewith | HENKEL CORPORATION (a Delaware corp.) (US) | 1981-04-15 | — | — | EP | claimed |
| US-4246376-A | PROTECTIVE COATINGS FOR METALS FROM AMINO-TYPE RESINS AND DIOLS AN | HENKEL CORPORATION (US) | 1981-01-20 | — | — | US | claimed |
| US-12570803-B2 | Composition, silicone polyether surfactant formed therefrom, and related methods and articles | DOW SILICONES CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| US-12540213-B2 | Composition and foamed polyurethane article formed therewith | DOW SILICONES CORPORATION (US) | 2026-02-03 | — | — | US | disclosed |
| EP-4259682-B1 | ISOCYANATE-REACTIVE COMPONENT, COMPOSITION COMPRISING SAME, AND FOAM FORMED THEREWITH | DOW SILICONES CORP (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4634259-A1 | HIGH STIFFNESS POLYURETHANE FOAM COMPOSITIONS | Dow Global Technologies LLC (US) | 2025-10-22 | — | — | EP | disclosed |
| US-20250257169-A1 | COMPOSITION, URETHANE PREPOLYMER, AND RELATED METHODS AND USES | DOW SILICONES CORP (US) | 2025-08-14 | — | — | US | disclosed |
| WO-2025106171-A1 | MULTILAYER COMPOSITE ARTICLES CONTAINING REINFORCED POLYURETHANE ELASTOMER SKINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-05-22 | — | — | WO | disclosed |
| US-4246376-A | PROTECTIVE COATINGS FOR METALS FROM AMINO-TYPE RESINS AND DIOLS AN | HENKEL CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4243818-A | High molecular weight products | HENKEL CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4229562-A | CURABLE ELASTOMER PRODUCES MOLDABLE MICROCELLULAR FOAM | HENKEL CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0017503-A2 | Gem-bis (hydroxymethyl) alcohols and mixtures thereof with diols, process for their preparation and a process for the preparation of polyurethanes therefrom | HENKEL CORPORATION (a Delaware corp.) (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4216344-A | High molecular weight polyol mixtures | HENKEL CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| US-4216343-A | High molecular weight polyhydric alcohols | HENKEL CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570803-B2 | Composition, silicone polyether surfactant formed therefrom, and related methods and articles | SGMS2, SGMS1, MSR1 | SPHK1 1350/4885CYP2D6 1758/4885LMNA 1138/4885 |
| US-12540213-B2 | Composition and foamed polyurethane article formed therewith | FGB, HBG2, HBG1 | SPHK1 4444/4885CYP2D6 1273/4885LMNA 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.